PPP011 - QT prolongation with Dr Dawson MacLeod
Jane is joined by Dawson MacLeod, a specialist in poisons information from the Victorian Poisons Information Centre.
Jane talks to Dawson about:
· The cardiac QT interval and its clinical significance
· Risk factors for QT prolongation, particularly in the context of drug interactions
· The best way to monitor and calculate a corrected QT interval from an ECG
· Medicines of greatest concern for QT prolongation
Further reading:
· Therapeutic Guidelines: Toxicology and Wilderness Figure 17.1: QT interval nomogram to assess risk of drug-induced torsades de pointes
· Isbister GK. Risk assessment of drug-induced QT prolongation Aust Prescr: 2015;38:20-4
· Rotella JA et al. Accuracy of QT interval measurement on electrocardiographs displayed on electronic 'smart' devices. Emerg Med Australas. 2016 Apr;28(2):187-92